Hypothesis: Homologous Recombination Depends on Parallel Search
نویسندگان
چکیده
منابع مشابه
Hypothesis: Homologous Recombination Depends on Parallel Search.
It is not known how a cell manages to find a specific DNA sequence sufficiently fast to repair a broken chromosome through homologous recombination. I propose a solution based on freely diffusing molecules that are programmed with sequences corresponding to those flanking the break site. In such a process, the target search would be parallelized.
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ژورنال
عنوان ژورنال: Cell Systems
سال: 2016
ISSN: 2405-4712
DOI: 10.1016/j.cels.2016.10.005